All Available Technologies

Summary:
Small camera/collection device that collects samples all along the surface of the esophagus, increasing disease detection rate.
Subcategory(s): healthcare

 

Summary:
Structural modification of a non-selective aminocyclohexanol-based heat shock protein 90 KDa (Hsp90) inhibitor led to a highly selective inhibitor of glucose regulated protein 94 kDa (Grp94). The new Grp94-selective inhibitor can be used to develop an effective therapy for the treatment of metastatic cancer and/or primary open angle glaucoma (POAG).
Category(s): therapeutics
Subcategory(s): small-molecules

 

Summary:
This invention describes the first selective inhibitor of heat shock protein 90 kDa beta (Hsp90β). The invented inhibitor selectively binds to the N-terminus of Hsp90β and may be developed for the treatment of cancers. The inhibitor was developed based on the sequence alignment of the N-terminal ATP-binding domains of Hsp90α and Hsp90β complexed with a non-selective Hsp90 inhibitor, which revealed Hsp90β-specific residues that were key to exploit the selectivity of the new inhibitor.
Category(s): therapeutics
Subcategory(s): small-molecules

 

Summary:
Most ZnO-nanostructure devices are fabricated using time-consuming nanomanipulation or one-by-one fabrication techniques, making them unattractive for large-scale production. Despite advantages in manufacturing cost and scalability, solutions-based processing has not produced high performing ZnO thin-film devices. This novel solutions-based process produces ZnO devices with shorter response times, lower device biases, and high light sensitivity.
Category(s): materials
Subcategory(s): lithography

 

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