The present invention provides decellularized cartilage (DCC) fragments or powder as a raw material component to be utilized for scaffolds and provides a microenvironment similar to that of native cartilage tissue. The DCC powder provides a platform technology upon which many cartilage, or even bone, tissue engineering scaffolds could be based.
A device for rapid dialysis of microliter volume liquid samples useful in laboratory-scale dialysis operations.
Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications. These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.
KU researchers have invented a high-pressure reactor equipped with an internal ultrasonic mixer that is useful for preparing nanomaterials and for conducting reactions with ozone and other reactive gases. The apparatus facilitates the use of supercritical carbon dioxide (CO2) as a solvent, allowing the advantages of the solvent properties of the supercritical fluid and the agitation achievable using ultrasonic energy.
This invention combines the strengths of two commonly used mouse strains (C57BL/6J and FVB/N) to obtain a preferable nuclear genome amenable to pronuclear injection for mouse transgenesis.
This invention provides an improved method for producing a novel interfacing capillary device that is less costly and more durable than existing sheathless devices. This simplified production method does not require sample dilution, etching, or precision hand tools, and is automated and reproducible.
Use of a genetic dereplication strategy eliminates major known SM biosynthetic pathways in Aspergillus nidulans, reducing the complexity of SM profiles and activating an abundance of silent SM gene clusters to enable identification of a new pool of fungal products for drug discovery.
The present invention employs a novel use of logic and data analysis tools to improve the efficiency of drug discovery.
This invention consists of a new hyphenated atomic force microscopy (AFM) technique with whispering gallery mode sensing (WGM), which provides the ability to measure the topography and refractive index of a material simultaneously.