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The technology presents a novel structural modification of an existing first generation Grp94 selective inhibitor to generate a second generation Grp94-specific scaffold which has greater affinity and selectivity compared to existing inhibitors and prevents unfavorable binding of other Hsp90 isoforms.

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Unique chemical derivatives invented by University of Kansas (KU) researchers that could be used to detect inhibitors of cellular efflux transporters and other agents. 

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This invention presents a novel series of modified cephalosporins, which exclusively target non-replicating mycobacterium tuberculosis.

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The developed technology aims to solve the water production and management problem in the cathode catalyst layer of a PEM Fuel Cell during a high current density operation.

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Continuous process for the controlled ozonolysis of organsolv lignin in a solvent consisting of short chain carboxylic acids or short chain carboxylic acid/water mixtures to yield aromatic monomer products including vanillin.

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This invention allows use of an efficient and stable oxygen evolution catalyst that facilitates water splitting without requiring noble metals or complicated synthesis methods. 

A safe method for the direct oxidation of methane and light alkanes to methanol and other oxygenates is disclosed.  Selective catalytic oxidation can be a transformative technology for using increasing abundant natural gas, bio-gas and other sources of low value hydrocarbons via gas to liquid process.

The present invention provides decellularized cartilage (DCC) fragments or powder as a raw material component to be utilized for scaffolds and provides a microenvironment similar to that of native cartilage tissue. The DCC powder provides a platform technology upon which many cartilage, or even bone, tissue engineering scaffolds could be based.

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A device for rapid dialysis of microliter volume liquid samples useful in laboratory-scale dialysis operations.

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Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications.  These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.

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